Immunotherapy with breast cancer

Several doctors and dentists like Sanoviv Dental know the importance of performing treatments focused on a specific area of ​​the body while taking into account the whole body, since everything is internally connected, that is why the action of immunotherapy drugs on some tumors, such as lung or melanoma, are already changing the prognosis of the disease. However, this therapeutic strategy, which stimulates the patient’s immune system against cancer, still does not work as effectively in breast cancer. These are some of the unknowns to solve.

The pending accounts of immunotherapy with breast cancer

These results are not yet definitive in metastatic patients with triple-negative subtype (breast cancer that does not have any last generation treatment) that have been tested in monotherapy an immunotherapeutic antibody in a group of patients who previously received other therapies and another group treated only with chemotherapy.

I have my doubts that they reach that 20% response rate, as in other tumors, says the oncologist. He explains that monotherapy is not giving the expected results against phase II studies where the combination of immunotherapy and chemotherapy has successfully reached 40% of patients.

The future of breast immunotherapy could be in combination with chemotherapy.

But still cannot conclude because there are some unknowns in the air: will immunotherapy be more effective in combination with chemotherapy/radiation therapy in breast cancer than in monotherapy? How can we select patients who will respond to immunotherapy, with other biomarkers? Is it better to use immunotherapy in the first line of treatment? The investigation will reveal them.

Breast cancer, a tumor with poor immunogenic response
What is clear is that breast cancer is very heterogeneous. Little has to do with the three major subtypes: the hormone receptor-positive tumors, the negative triples. Three different diseases, with different forecasts and treatments.

Besides, breast tumors are also different concerning their immunogenicity or faculty to warn the immune system and go behind lung or melanoma tumors.

But among them, the negative tripe is the one with the most capacity to activate the body’s defenses because it has more genetic mutations, which makes it more receptive to future target treatments and immunotherapy.

Therefore, it is in this type of cancer that immunotherapy research is focused, although there are also ongoing studies on positive hormone receptor tumors.

Breastfeeding and breast cancer

According to doctors and dentists like Samaritan Dental know that to have a healthy body as a healthy and robust tooth, it is essential to be well nourished, now a report from UNICEF emphasizes that breastfeeding from the minute zero is not only good
for the baby, it is also for the health of the mother.

Improve breastfeeding in the world for all babies
Create adequate and positive environments for breastfeeding. Measures such as drafting laws that guarantee that paternity permits and being able to breastfeed at work are critical. Also, hospitals and health experts inform, allow and facilitate breastfeeding after delivery. In Spain, every day is more common than in health centers after giving birth, and the midwife helps the new mother to breastfeed. The rite is usually born, put the baby skin to skin and teach the newborn and mother to mate, something that should always happen, but it does not occur on all sides, as explained by UNICEF and reiterated a few weeks ago the World Health Organization. Health. Experts point out that there must also be more restrictions on the marketing of artificial milk.

The father’s support in breastfeeding. UNICEF emphasizes that husbands and couples cannot underestimate this practice, so their involvement in the process is necessary.

Breastfeeding is not only good for babies born full-term. The organization emphasizes that breastfeeding from birth would help all babies. This organization, together with the WHO, executed a 10-step guide last month in which it states: The original guidelines were aimed at the ideal birth, to babies born at term (in the 39th week of gestation). In contrast, these new indications are also directed to premature babies, underweight babies or sick people. For example, in Spain, it would improve the health of many newborns. Each year about 29,000 children are premature, that is, before week 37, and represent 75% of hospital admissions in neonates, according to the latest data offered by the Spanish Society of Neonatology. In Europe, there are 500,000 who do it annually.

Experts who support difficulties before breastfeeding. It is known that there is no right or lousy breast milk, but many times some mothers find themselves with a wall when breastfeeding their little ones. Problems related to hooking, stress, poor performance, among others. UNICEF makes a complaint to the countries to make specialized assistance available to women in breastfeeding to help cope with possible complications.

Unless medically indicated, never give a newborn a liquid other than breast milk.

That mother and son are together from zero and 24 hours. A technique very used after childbirth and that involves placing the newborn on the chest of one of their parents. The benefits of skin with skin or kangaroo method are many. It is a method that does not need technology, but it is of great help, especially for premature children (born with less than 37 weeks) or who are born with low weight, the authors say, concluded the study 20 years analyzing the kangaroo method. Traditional care, Besides, to be effective, it also requires that the mother breastfeed her child whenever possible and that a strict follow-up of both is carried out at least during the first year of life. This method can lower the number of premature babies who die.

Breast and prostate cancer

Just as we constantly go with our  affordable dentist in mexico to have the best oral health, specialists advise routine checkups and diagnostic tests to detect any presence of cancer in time.

The Dominican Republic has a high incidence of cancer, with breast cancer being the number one among women and prostate cancer being the first in men.

In the second place among the females is cervical cancer, which according to the oncologist, is a shame because it is preventable with an effective prevention and education campaign.

Other types of cancer that also have incidence among the population are the lung and primary malignancies of unknown origin, and in all of them, the guarantee of achieving higher rates of cure is in the early diagnosis.

The specialist referred to the issue during an interview before the official launch in the country of novel tumor markers that allow diagnosing the risk of prostate, lung and ovarian cancer, as well as primary malignancies of unknown origin, through a blood test.

It was explained that these are very innovative and non-invasive tumor markers that will help physicians to find a possible malignancy in less time, as well as to avoid unnecessary explorations that patients must currently undergo to determine whether or not they have cancer.

The specialists explained that the panels of specific, non-invasive markers are available in the central clinical laboratories of the country, through the Dominican company, which distributes them to Central America and the Caribbean.

They highlighted that these blood and urine tests are a great tool to detect cancer early in patients with a previous finding that suggests malignancy and that they should be biopsied for confirmation.

They indicated that these tests should be part of the routine checkup of women after the age of 25 and of all those who belong to one of the risk groups for each type of cancer, such as smoking patients over 55 years of age, or women over 40 with a family history of breast or ovarian cancer.

Diet and exercise behind breast cancer

Dentists such as EG Dental know that environmental factors, diet or lifestyle have a significant effect on people’s lives, both for good and evil as is the development of breast cancer, according to scientific evidence.

According to the epidemiological data of 2018, the incidence of breast cancer in Spain in about 26,000 women, which is approximately a new case of breast cancer every 20 minutes., Hence the need to delve into the biology of the disease. Thus, carcinogenesis has focused on the different presentations of the seminar: what factors, both internal and external, can trigger the proliferation of tumors. The knowledge of the mechanisms of appearance and the dynamic genomic changes of this disease is making it possible to identify tumor biomarkers. In other words, we can modify the natural history of the disease thanks to little knowledge and research.

On the other hand, the head of the Breast Pathology Unit has explained that hormone replacement therapy, which improves the quality of life of women with the climacteric syndrome, is associated with an increased risk of breast cancer if prolonged by more than two years. It has also referred to the consumption of phytoestrogens in the diet (isoflavones and lignans especially present in legumes and some grains) for its preventive effect against this disease.

Food and exercise

Regarding external or environmental factors, there are several, from diet to radiation, in which science has established an association with a higher probability of developing tumors. As explained, nutrition is emerging as one of the elements that can help prevent the onset of breast cancer.

The role of diet in breast cancer has been investigated, both by analyzing foods individually and by groups of foods or nutrients. It has been found that the consumption of alcohol increases the risk, as well as that of fat and, especially the saturated one, explains the doctor, who clarifies that, fortunately, many foods show a protective effect as the consumption of vegetables and grains rich in fiber. The results of this study indicate that the Mediterranean diet reduces the risk of breast cancer by 6% in postmenopausal women.

Concerning alcohol or tobacco, although traditionally they have not been considered causes of breast cancer, there is currently no doubt that both increases the risk of breast cancer in about 10% and physical exercise reduces the risk of breast cancer by 25%.

Breast cancer can also appear in men

Prevention is the best cure for all diseases, and many people are made e gastric sleeve Tijuana Mexico to avoid all the conditions that cause obesity, as well as early detection of breast cancer increases life expectancy.

Nationwide there are about 60 deaths from breast cancer in men, revealed the Public Health coordinator of the Puebla Delegation of the Mexican Institute of Social Security.

These cases can have their origin by not eating a healthy diet, little physical activity, alcoholism, smoking, and obesity, as well as little assistance with a doctor when a symptom is detected.

In this context, if a man detects something abnormal in his breast, he should go to the preventive medicine services so that a diagnosis is made, and if required, a mammogram will be performed.

In the case of women, the institute contemplates approximately 40 thousand mammograms per year, which aims to detect and treat early malignant tumors in the breasts of women between 40 and 69 years of age.

Each year the coverage radius is 30% of the female population; 10% in an age range of 40 to 49, and the other 20% in women between 50 to 69 years; This proportionality occurs because of the lower the risk of suffering an anomaly.

Risk factor’s

The risk factors can be: a history of a family member with breast cancer, age 40 or older, if the first menstrual period was before age 12, use hormonal contraceptives for more than ten years, have had their first child after 30 years, not breastfeeding and obesity.

Breast cancer is very aggressive, so early detection represents a high possibility of cure and thanks to campaigns has achieved a reduction in the death rate of 13%.

Regarding ionizing radiation using different means of radiodiagnosis, carcinogenesis is one of the risks of this type of waves, although the risk-benefit balance in favor of performing tests such as mammography is not discussed in the context diagnosis. In addition, the dose of radiation has decreased considerably with the implementation of digital mammograms and currently a typical exploration does not reach 4mSv, lower than in other explorations of extended use such as spine radiographs.

Endocrine disruptors

The meeting has also addressed the effects that substances that alter the metabolism and that are considered endocrine disruptors can have for breast cancer. This is the case of cadmium, whose main source of exposure is tobacco. Likewise, the possible risks of oral contraceptives or infertility treatments have been analyzed.

The “Why” and “How” of Root Canal Treatment

Root canal is often described as a dental treatment procedure which targets decayed tooth. However, this much will not really help- especially if you are looking forward to resorting to this treatment soon. It is very important to study about the treatment properly before heading towards the dentist’s clinic for the root canal. It is often said that this particular procedure (i.e. root canal) is not explained properly to patients and that doctors often perform this treatment although it is not absolutely necessary. Today, within the scope of this post, we will be discussing root canal in detail so that it becomes easier for you to, at least, have an idea whether you need the help of this treatment to address your present dental concerns or not.

When is the treatment performed?

If your tooth has already started showing signs of decay, it would be great if you are considering a root canal treatment since it will prevent further decay and the eventual loss of your tooth.

The root canal is channel (shaped in the form of a canal) which runs from the surface of the tooth to the tooth itself. Te channel is filled with several soft tissues. It consists of the primary nerve tissue in tooth.

The procedure describe turn in detail

The canal contains the soft tissue, which, in turn, contains the nerve tissue. So the entire treatment requires the inclusion of an anesthetic who numbs the tooth and its surrounding areas. The dentist will then drill down the tooth to remove its infected tissues. When the canal plunges in to the actual stem, the dentist makes use of a manual device to empty all the soft tissues. Once the tissue has been extracted, the empty space is filled with rubbery cement.

The dentist takes an ex-ray of the rubbery tooth and makes sure that there are no empty air pockets in the tooth. Huggins protocol dentist eliminates the cement just layered over the treated tooth and refills it.

Patients might as well feel moderate pain after the treatment. There is a general notion that the treatment involves a lot of pain since it has to with the removal of nerve endings.

How to find clinics

There are several clinics offering Root Canal Treatment. Make sure you are zeroing in on a reliable name after conducting proper research on the background and the reputation earned by the